“Rejuvenating the brain might hold the line or possibly slow decline a bit, but not return our brain back to where it was when we were 20. That’s way beyond the science as it exists,” writes Dr. William Brown.

“In a nutshell, that’s what rejuvenation is all about: making old cells, old systems, old organs including our brains, young again. Or at least, that’s the hyped hope,” writes Dr. William Brown

“Do some patients with mid-to-late-stage dementia have abnormal electrical activity in their brains that contributes to their cognitive decline?” writes Dr. William Brown.

“Performance in any sport depends on physical and neural fitness, acquired skills and stamina,” writes Dr. William Brown. “There’s also the factor of the cumulative effects of injuries affecting muscles and joints.”

“Why neanderthals went extinct isn’t clear, writes Dr. William Brown. “Were their numbers simply too small to survive bad seasons for plants and animals to hunt?”

“ChatGPT came out in late 2022 and look what’s happened since. Plot the curve for human intelligence and AI’s intelligence and the differences are obvious,” writes Dr. William Brown.

Mini-brains, writes Dr. William Brown, “replicate in amazing detail the earliest development of the six-layer cortex of human neocortex, typical of human embryos at equivalent stages of embryonic development.”

“Future conflicts are breeding now because of what happened in the past and continues in the present and will be bitterly remembered in the future,” writes Dr. William Brown.

“Politicians have a habit of hanging on long after their best-before dates, believing the country can’t get by without them. That’s a sign of cognitive impairment, not an encouragement,” writes Dr. William Brown.

“Transmissible prion is extremely stable and very hard to destroy with chemical disinfectants or heat — far more so than for the case of viruses and bacteria,” writes Dr. William Brown.

“An accelerating expansion of the universe without any obvious cosmic brakes … is a universe whose matter is so dispersed that stars can’t form, with the result that the universe eventually goes dark and cold with no place for life,” writes Dr. William Brown.

“For many, it’s AI’s uncanny ability to talk naturally and build relationships with its human users that’s perhaps the most unnerving part, but also for many users, AI’s allure,” writes Dr. William Brown.

“Bipedalism freed up the arms and especially the hands for other tasks such as tool-making, creating art and music, all of which was enabled and fostered by increasingly larger brains,” writes Dr. William Brown.

“Human society is like chimpanzee society — tribalistic and prone to violence. A list of conflicts from world wars to endless regional conflicts and violence within our own country makes the point,” writes Dr. William Brown.

“No wonder some dogs hang out with other dogs and humans who might offer companionship, safety, warmth, food and water. Wouldn’t we in similar circumstances?” writes Dr. William Brown.

“The whole experience was much better than commercial flying. We could see migrating birds in season, the unfolding country we were crossing, and overall travel times rivaled commercial flying,” writes Dr. William Brown.

“If controlled fire was a huge plus for neanderthals 400,000 years ago, how far back does controlled fire go?” writes Dr. William Brown.

“These days, the nature of consciousness is hotly debated by several competing groups, with no consensus or clarity emerging in the debates between them,” writes Dr. William Brown.

“Driving everything in my quest for understanding nature have been recuring themes for me,” writes Dr. William Brown, citing the universe, human evolution, the rise of AI and more.

“Colonizing Europeans often encountered what they considered primitive peoples,” writes Dr. William Brown. “Yet, within a few generations, those so-called ‘primitives’ mastered European languages, cultures and technologies.”

“My guess is that had AI been trained on similar challenging math problems, it wouldn’t have taken long before AI mastered other questions posed by top notch mathematicians,” writes Dr. William Brown.

“The picture of human evolution, and indeed the evolution of most species, may look very different by the mid-century mark and beyond. That’s what makes the story so intriguing for me,” writes Dr. William Brown.