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Dr. Brown: New drugs and the ongoing battle against Alzheimer’s
Like Oliver Sachs, I eagerly look forward to the weekly arrival of the next issue of the journal Nature. Last week a piece written by Paul Nurse caught my eye. He quoted his
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Like Oliver Sachs, I eagerly look forward to the weekly arrival of the next issue of the journal Nature. Last week a piece written by Paul Nurse caught my eye. He quoted his
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Sometimes, a rare disease can teach us a lot about treating more common diseases. Such is the case for a disease called transthyretin amyloidosis, which in its autosomal dominantly transmitted form, is rare
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For most of us who have been sweltering in Ontario’s summer heat wave, the latest surge in infections in Israel seems too far away to worry. But Israel may be the canary in the mine

Unlike simple cells such as archaea and bacteria, viruses such as SARS-CoV-2 (which causes COVID) are unable to make copies of themselves without host cells to exploit. Like most viruses, SARS-CoV-2 is a
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No one knows when storytelling began but it would have required symbolic thought and language and the cognitive ability to imagine and literally “talk about” the past, present and future. Modern humans were probably not
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At the most basic level, this pandemic has always been about a battle between hordes of mutating viruses and billions of human hosts, with no clear victor or end as yet in sight.
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When I was a medical student, the dean of Medicine at Western University presented the history of a young man who had a malignant melanoma with metastases to his liver (based on a laparoscopic
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For much of human history, the Earth was firmly planted at the centre of the known universe – a reasonable assertion given that the sun regularly rose in the east and set in
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About 100,000 years ago, 36 stocky people walked along a beach in southern Spain leaving footprints behind in the sand which later fossilized. Most were made by adults and a few by children

For most healthy, middle-aged and especially younger people, infection with COVID-19 has been a non-event – a positive PCR test with few, if any symptoms to show for the infection. But for older folk
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A week ago. the Sunday New York Times was in full celebration mode, festooned with plenty of photos of packed indoor and outdoor activities, open restaurants, bars and theatres, admittedly with some residual distancing and
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The U.S. Food and Drug Administration has approved aducanumab to treat Alzheimer’s disease. Like other similar drugs, it was designed to rid the brains of Alzheimer's patients of buildups of amyloid and, more importantly, slow the progression of
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Try prodding yourself with your fingers – feels solid enough doesn’t it – maybe a little too much here and there, but solid. You’ll swear to it. What if I told you that you
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Every airplane I’ve flown had a magnetic compass located in plain view well above the panel. With it, I could determine my magnetic heading should vacuum-driven devices such as the directional gyro or horizontal
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During this pandemic we witnessed selfless behaviour by thousands of health care workers around the globe, who at great risk to themselves, struggled daily to save lives in a battle with a virus,

Back pain is one of the banes of humanity. The cause, especially in the later decades of life, is usually cumulative degenerative changes in the lower spine involving the vertebral bodies, the discs

We need maps, whether the maps embedded in our brain’s temporal and parietal lobes based on past experiences, tried and true paper maps or these days embedded in GPS devices in our cars

After more than a year of turmoil, suffering and death, there’s been one shining light in this pandemic – the rapid design of several highly effective vaccines. Troubles associated with the rollout of the

When we were children and teenagers, we often fell. And if we had much to do with rough and tumble sports, falls were part of the game with nothing more to show for

Too little, too late and sometimes wrong: That about describes the state of the pandemic for most countries around the world. Thank goodness for success stories such as the aggressive vaccination programs in Israel
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The story of human origins is very much a work in progress, mostly for want of fossils and artifacts to fill in remaining gaps in the record. But as matters stand, the story

Dr. William Brown is a professor of neurology at McMaster University and co-founder of the Infohealth series at the Niagara-on-the-Lake Public Library. In 1940, the British navy was very short of aircraft
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Dr. William Brown is a professor of neurology at McMaster University and co-founder of the Infohealth series at the Niagara-on-the-Lake Public Library. ________________________________________ We learned last week that much of the brain is
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Dr. William Brown is a professor of neurology at McMaster University and co-founder of the Infohealth series at the Niagara-on-the-Lake Public Library. ____________ Toward the end of his BBC series “The Ascent of Man,” Jacob Bronowski
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Our brain is enormously complex and capable of great feats of imagination, creation, ingenuity and understanding the world around us. Yet our brains can be mysteriously opaque about how they go about much

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